Citation: Guo Chen CHI, Zhong Biao ZHANG, Xiao Hua Xu, Ru Yu CHEN. Stable Send-ketals of 3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-2'-Ketouridine[J]. Chinese Chemical Letters, ;1998, 9(11): 989-992. shu

Stable Send-ketals of 3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-2'-Ketouridine

Insitute of Elemento-Organic Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071

Received Date: 7 May 1998

A series of stable semi-ketals were obtained via the reactions of 3',5'-0-(tetraisopropyldisiloxane-l, 3-diyl)-2'-ketouridine 1 with primary alcohols. In the addition reaction, only a single diastereomer was observed. The configuration of 3b was confirmed by X-ray diffraction.
- Nucleoside,
- ketonucleoside,
- semi-ketal,
- configuration
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