Citation: Li Ren JIN, Jian Liang YE, Yong XIE, Jiang Hong SHI, Pei Qiang HUANG, Kyeong Eun JUNG, Hong LIM. Asymmetric Synthesis of Polyhydroxy Pyrrolidinonyl Nucleoside Analogues from Tartaric acid[J]. Chinese Chemical Letters, ;1999, 10(7): 543-546. shu

Asymmetric Synthesis of Polyhydroxy Pyrrolidinonyl Nucleoside Analogues from Tartaric acid

1.
Department of Chemistry, Xiamen University Xiamen, Fujian 361005;
2.
Dongbu Advanced Reseach Institute, Daeduck Science Town, Taejon Korea

Received Date: 15 January 1999

Fund Project: We are grateful to A. R. Fund of Han-Nong Corporation, Korea the National Natural Science Foundation of China and the Ministry of Education of China for the financial support.

Asymmetric synthesis of novel optically active nucleoside analogues 7 from natural tartaric acid is described. In the given nucleoside analogues an optically active polyhydroxy pyrrolidinonyl ring is in place of the tetrahydrofuran ring.
- Nucleoside,
- pyrrolidinone,
- asymmetric synthesis
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