Citation: Hui Lan CHEN, Hong YAN, Wen Xia TANG. AN IMPROVED METHOD TO SYNTHESIZE VITAMIN B₁₂ COENZYME ANALOGUES CONTAINING 2'-DEOXYNUCLEOSIDE[J]. Chinese Chemical Letters, ;1992, 3(4): 245-246. shu

AN IMPROVED METHOD TO SYNTHESIZE VITAMIN B₁₂ COENZYME ANALOGUES CONTAINING 2'-DEOXYNUCLEOSIDE

Department of Chemistry and Coordination Chemistry Institute Nanjing University Nanjing 210008

Received Date: 5 December 1991

A new vitamin B₁₂ coenzyme analogue 2’,5’-dideoxyuridinyicobalamin and two other 2’,5’-dideoxynucleosidecobalamins of adenosyl-and thymidyl-were synthesized by an improved method, It consists in direct tosylation of the nucleoside and followed by reaction with reduced hydroxocobalamin(vitamin B₁₂). All the 2’-deozynucleoside derivatives were characterized by UV-Vis and ¹HNMR spectroscopy
1. [1]
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2. [2]
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3. [3]
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4. [4]
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5. [5]
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6. [6]
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7. [7]
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10. [10]
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12. [12]
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13. [13]
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14. [14]
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15. [15]
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16. [16]
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17. [17]
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18. [18]
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19. [19]
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20. [20]
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