Citation: Bo WANG, Hong Zhu MA, Qi Zhen SHI. Synthesis of Optical Active 2-Arylpropionic Acids[J]. Chinese Chemical Letters, ;2001, 12(7): 571-574. shu

Synthesis of Optical Active 2-Arylpropionic Acids

Department of Chemistry, Key Laboratory of Physical Inorganic Chemistry of ShanXi Province, Northwest University, Xi'An 710068

Received Date: 2 January 2001

(S)-2-(6'-methoxyl-α-naphthyl) propionic acid ((S)-Naproxen, ee 99%) has been prepared starting from (6-methoxyl-α-naphthyl)propan-1-one and D-sorbitol under SmCl₃catalysis.
- Propionic acid,
- (S)-naproxen,
- D-sorbitol,
- catalysis.
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