Citation: Tao, Laurence H. HURLEY. Synthesis of 5,10,15,20-Tetra(N-methyl-6-quinolyl)-21,23-dithiaporphyrin Chloride as Cationic Core-modified Porphyrin[J]. Chinese Chemical Letters, ;2004, 15(11): 1261-1264. shu

Synthesis of 5,10,15,20-Tetra(N-methyl-6-quinolyl)-21,23-dithiaporphyrin Chloride as Cationic Core-modified Porphyrin

Tao ^1, ,
Laurence H. HURLEY ²

1.
Department of Organic Chemistry, China Pharmaceutical University, Nanjing 210009;
2.
College of Pharmacy and Arizona Cancer Center, University of Arizona, Tucson AZ 85742, USA

Received Date: 23 September 2003

Fund Project: We are grateful for the financial supports from the National Institutes of Health (CA49751) and The National Cooperative Drug Discovery Group grant from the National Cancer Institute (CA67760).

First cationic 6-quinolyl substituted dithiaporphyrin was synthesized using Skraup quinoline methodology from thiaporphyrin bearing 4-acetamidophenyl prepared by condensation reaction of aromatic aldehyde with pyrrole.
- Porphyrin,
- thiaporphyrin,
- telomerase inhibitor,
- dilithiophen
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