Citation: Jun Gui DAI, Lin YANG, Jun Ichi SAKAI, Masayoshi ANDO. A Taxatetraene from Microbial Transformation of Sinenxan A[J]. Chinese Chemical Letters, ;2005, 16(6): 736-738. shu

A Taxatetraene from Microbial Transformation of Sinenxan A

1.
Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050;
2.
Department of Chemistry and Chemical Engineering, Niigata University, Ikarashi 2-8050, Niigata 950-2181, Japan;
3.
College of Life and Environmental Sciences, The Central University for Nationalities, Beijing 100081

Received Date: 15 June 2004

Fund Project: This work is supported by the National Natural Science Foundation of China (Project No. 30100230) and the Japan Society for the Promotion of Science (Project No. 1300127).

Sinenxan A[2α, 5α, 10β, 14β-tetraacetoxytaxa-4(20), 11-diene, 1] was biotransformed by a filamentous fungus, Aspergillus niger JCM 5546, and an unusual taxatetraene[2α,5α-acetoxytaxa-4(20), 10(11), 12(18), 13(14)-tetraene, 2], together with two known products,10β-deacetyl sinenxan A (3) and 10β, 14β-dideacetyl sinenxan A (4) were produced.
- Aspergillus niger,
- sinenxan A,
- taxatetraene,
- biotransformation
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1.
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