Citation: Li Ming DU, Jing ZHOU, Qing Qin XU, Zhe Feng FAN, Rong YUAN. Study on Fluorescence Property of Sparfloxacin Derivatizing System and its Application[J]. Chinese Chemical Letters, ;2000, 11(3): 255-258.
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In acid medium,sparfloxacin is oxidized by nitrous acid,then reacts with hydrobromic acid to form a new fluorescence substance,which can emit the strong fluorescence,which is 151 fold more than that of sparfloxacin itself. By this,a new sensitive method for the determination of sparfloxacin in human urine by derivative-synchronous fluorescence is presented with good results.
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