Citation: Xiu Wei YANG, Chen Ting ZOU, Masao HATTORI. Harpagometabolins I and II,Two New Metabolites from Harpagoside by Human Intestinal Bacteria[J]. Chinese Chemical Letters, ;2000, 11(9): 779-782.
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Harpagoside, which is one main iridoid constituent of the dried roots of Scrophularia ningpoensis Hemsl., was biotransformated by bacteria isolated from human fecal flora and three metabolites were obtained.The structures of the metabolites, including two new alkaloids, named harpagometabolins I (1) and Ⅱ (2), and a known alkaloid acubinine B (3), were identified by chemical methods and the spectroscopic evidences.
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