Citation: Wu Yan ZHANG, Ji Yu GUO, Xiao Tian LIANG. Studies on Agarofurans Ⅱ.Stereoselective Synthesis of 1α-and 1β-Methyl Agarofuran[J]. Chinese Chemical Letters, ;1997, 8(6): 491-492. shu

Studies on Agarofurans Ⅱ.Stereoselective Synthesis of 1α-and 1β-Methyl Agarofuran

Insitute of Materia Medica, Chinese Academy of Med. Sci. & Peking Union Med. College, Beijing 100050

Received Date: 3 February 1997

Fund Project: This work was supported by the National Natural Science Foundation of China.

1α-and 1β-methyl agarofuran 1 and 2 were stereoselectively synthesized,the key intermediates being synthesized through stereoselective Robinson annulation.The conjugated double bond was reduced in an improved way.Alkylation of imine 7 with enone 8,9,10 was performed.
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