Citation: Jian Kui ZHAO, Yan Guang WANG. A Facile and Efficient Synthesis of N,N-Dimethylarylamines from Aryl Bromides[J]. Chinese Chemical Letters, ;2002, 13(12): 1149-1151. shu

A Facile and Efficient Synthesis of N,N-Dimethylarylamines from Aryl Bromides

Department of Chemistry, Zhejiang University, Hangzhou 310027

Received Date: 25 March 2002

Catalytic amination of aryl bromides with in situ generated dimethylamines from N,N-dimethylacetamide (DMA) has been successfully carried out using Ni(Phen)Cl₂ as catalyst. Both electron-rich and electron-poor aromatic system reacted smoothly under the conditions to give N,N-dimethylarylamines in good yields.
- Amination,
- nickel-catalyzed,
- cross-coupling reaction,
- N,N-dimethylarylamine
1. [1]
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2. [2]
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3. [3]
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