Citation: Zhao Yang WANG, Jia Ling CUI, Bao Shan DU, Qing Hua CHEN. Studies on New Additions to 5-Methoxy-2 (5H)-Furanone:1, 4-Addition of Grignard Reagents, and 1,3-Dipolar Cycloaddition of Silyl Nitronates[J]. Chinese Chemical Letters, ;2001, 12(4): 293-296. shu

Studies on New Additions to 5-Methoxy-2 (5H)-Furanone:1, 4-Addition of Grignard Reagents, and 1,3-Dipolar Cycloaddition of Silyl Nitronates

1.
Department of Chemistry, Beijing Normal University, Beijing 100875;
2.
Present address:Dept. of Chem., South China Nor. Univ, Guangzhou 510631;
3.
Present address:School of Pharm., Beijing Univ, Beijing 100083

Received Date: 14 August 2000

Fund Project: This work was supported by the NNSFC (No.29672004).

1,4-Addition reaction of Grignard's reagent to 5-methoxy-2 (5H)-furanone 1 was accomplished, which provided a new possible route for synthesizing β-alkyl-γ-alkyloxy-γ-butyrolactone. A novel concise method of preparing fused heterocyclic compounds was offered by 1,3-dipolar cycloaddition reaction of silyl nitronates to 1.
- Michael addition,
- Grignard reagent,
- 1,3-dipolar cycloaddition,
- silyl nitronates.
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