Citation: Hui GUO, Wu Xin ZOU, Qi JI, Ji Ben MENG. Synthesis and Photochromic Properties of Azido Analogues of Spiropyran and Spirooxazine as Nucleic Acid Labeling Reagent[J]. Chinese Chemical Letters, ;2005, 16(6): 751-754. shu

Synthesis and Photochromic Properties of Azido Analogues of Spiropyran and Spirooxazine as Nucleic Acid Labeling Reagent

Department of Chemistry, Nankai University, Tianjin 300071

Received Date: 5 July 2004

Fund Project: The authors thank the National Natural Science Foundation of China for financial support. (Grant Nos. 20072018 and 20372039).

A series of photo active azido analogues have been synthesized and their photochromic properties have also been investigated by UV-Vis spectrum. It will be used for the rapid and reliable preparation of large amounts of stable, non-radioactive labeled DNA and RNA hybridization probes. And it is supposed to be easily detected for its photochromic properties.
- Nucleic acid,
- photochromic,
- label,
- azido,
- spiro
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