Citation: Ming LEI, Cheng MA, Yan Guang WANG. Solid-Phase Total Synthesis of 1-β-Methylcarbapenem[J]. Chinese Chemical Letters, ;2003, 14(1): 6-8. shu

Solid-Phase Total Synthesis of 1-β-Methylcarbapenem

Department of Chemistry, Zhejiang University, Hangzhou 310027

Received Date: 5 April 2002

Fund Project: This work was financially supported by the National Natural Science Foundation of China (No.29972037).

A 1-β-methylcarbapencm analogue 6 was synthcsized on polystyrene-dicthylsilane resin (PS-DES) using 2-azetidinone bearing with 2-oxazolidonc chiral auxiliary as starting matcrial.
- Solid-phase,
- synthesis ofβ-lactam,
- carbapenem,
- antibioties
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