Citation: Hua Yin LIU, Guang Fu YANG, Hua Zheng YANG. Synthesis and Structure of 3-Aryl-5-cyano-6-methylthio pyrimidine2,4-diones[J]. Chinese Chemical Letters, ;1999, 10(3): 191-192. shu

Synthesis and Structure of 3-Aryl-5-cyano-6-methylthio pyrimidine2,4-diones

State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071

Received Date: 16 October 1998

Fund Project: This study was supported by grants from the National Natural Science Foundation of China (No:29702006) and the Special Natural Science Foundation of Tianjin.

The title compounds of 3-aryl-5-cyano-6-methylthiopyrimidine2.4-diones weresynthesized by the reaction of ethy1 2-cyano-3.3'dimethylthioacrylate with arylureas.The compound (Ar=p-CH₃OC₆H₄) was recrystallized in acetone/petroleum in space group P2_(1/n) with a=1.1602 (2), b=1.5921(3), c=1.3918 (3)nm.β=94.38 (3)° for Z=8.R=0.054.The X-ray analysis showed that there is H-bond interaction among molecules.
- Synthesis,
- crystalline structure
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