Citation: Xu Feng LIN, Cheng MA, Yan Guang WANG. A Facile Synthesis of Spin Labeled 4'-Epi-N-Trifuoroactyldaunomycin Derivatives[J]. Chinese Chemical Letters, ;2001, 12(8): 665-666. shu

A Facile Synthesis of Spin Labeled 4'-Epi-N-Trifuoroactyldaunomycin Derivatives

Department of Chemistry, Zhejiang University, Hangzhou 310027

Received Date: 8 February 2001

The spin labeled 4'-Epi-N-trifuoroacetyldaunomycin derivatives 6-7 were conveniently synthesized from daunomycin in middle yield. The key steps were the protection of compd. 5 at 9-position and nucleophilic displacement of 5 with R.COOH and DBU at room temperature.
- Spin labeled,
- daunomycin,
- antitumor,
- synthesis.
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