Citation: Jiu Yu LIU, Hui Yuan GUO. Synthesis of Quinolone Analogues: 7-[(2S, 4R)-2-Aminomethyl-4-hydroxypyrrolidin-1-yl] Quinolones[J]. Chinese Chemical Letters, ;2004, 15(5): 535-538. shu

Synthesis of Quinolone Analogues: 7-[(2S, 4R)-2-Aminomethyl-4-hydroxypyrrolidin-1-yl] Quinolones

Jiu Yu LIU ,
Hui Yuan GUO

Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050

Received Date: 17 April 2003

New quinolone derivatives of 7-[(2S, 4R)-2-aminomethyl-4-hydroxypyrrolidin-1-yl] quinolone-3-carboxylic acids were synthesized by condensation of 7-halo substituted quinolone-3-carboxylic acids with (2S, 4R)-2-aminomethyl-4-hydroxypyrrolidine. These compounds were characterized by FAB-MS and ¹H NMR.
- Pyrrolidine,
- quinolone,
- synthesis
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