Citation: Jia Xi XU, Zhi Hui QIN, Jun Y. ANG, Meng Shen CAI. DESIGN AND SYNTHESIS OF ANALOGS OF THE SCHISTOSOMA MANSONI P28 ANTIGENIC PEPTIDE P141[J]. Chinese Chemical Letters, ;1995, 6(6): 465-466. shu

DESIGN AND SYNTHESIS OF ANALOGS OF THE SCHISTOSOMA MANSONI P28 ANTIGENIC PEPTIDE P141

School of pharmaceutical Sciences, Beijing Medical University, Beijing 100083

Received Date: 6 December 1994

Four analogs of the Schistosoma mansoni P28 antigenic peptide P141 were designed according to the similarity in the structure of the amino acid residues and Chou-Fasman's secondary structurally conformational parameters P_α, P_β and Pt values, also according to the hydrophilicity of the amino acid residues.They were syntliesized by using Merrifield solid phase peptide synthesis method.ELISA experiments showed their antigenicity.
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