Citation: Zao Ying LI, Yue Ning ZHANG, Zhen Ting GAO, Yi LIU, Xun Jin ZHU. Synthesis, Characterization and Biological Activities of Novel Water-soluble Metalloporphyrins[J]. Chinese Chemical Letters, ;2001, 12(12): 1085-1088. shu

Synthesis, Characterization and Biological Activities of Novel Water-soluble Metalloporphyrins

Department of Chemistry, Wuhan University, Wuhan 430072

Received Date: 20 April 2001

Fund Project: Financial support from the National Natural Science Foundation of China is gratefully acknowledged (No.29972035).

The synthesis, characterization, and biological activities of a series of metal porphyrins were described. The complexes 3a~3e were prepared from the reaction of compound 2 with M(OAc)₂ in CHCl₃, and the treatment of 3a~3f with pyridine gave corresponding complexes 4a~4f. These new compounds were identified by absorption spectroscopies, ¹H NMR and elemental analysis. The results of biological activity testing revealed that 4a and 4c had stronger inhibiting action for Escherichia coli (CCTCC AB91115).
- Water-soluble metalloporphyrin,
- synthesis,
- structure characterization,
- biological activity testing
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