Citation: Xing LU, Yue WANG, Hai Yuan ZHANG, Chun Ji NIU, Jia Zuan NI. Tb(Ⅲ) Speciation in Human Blood Plasma by Computer Simulation[J]. Chinese Chemical Letters, ;2001, 12(9): 809-812.
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A multi-phase model was developed and Tb(Ⅲ) speciation in human blood plasma was studied. At a concentration below 3.744×10-4mol/L (or at the concentration), Tb(Ⅲ) is mostly bound to phosphate to form precipitate of TbPO4. As the concentration of Tb(Ⅲ) increases,phosphate is exceeded and another kind of precipitate of Tb2(CO3)3 appears. Among soluble Tb(Ⅲ) species, Tb(Ⅲ) mainly distribute in [Tb (Tf)] at low concentration and in [Tb (HSA)], [Tb2(Tf], [Tb (IgG)], [Tb (Lactate)]2+, [Tb (CitArgH)] and free Tb(Ⅲ) at high concentration.
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Keywords:
- Terbium(Ⅲ),
- speciation,
- human blood plasma,
- computer simulation
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