Citation: Wei Yi CHEN, Jun LU, Ya Wen ZHANG, Zong Xuan SHEN. Enantioselective Reduction of Achiral Ketones with NaBH₄/I₂ Catalyzed by (S)-Ferrocenyl Amino Alcohols[J]. Chinese Chemical Letters, ;2002, 13(10): 931-932. shu

Enantioselective Reduction of Achiral Ketones with NaBH₄/I₂ Catalyzed by (S)-Ferrocenyl Amino Alcohols

Department of Chemistry and Chemical Engineering, Suzhou University, Suzhou 215006

Received Date: 4 January 2002

The reduction reagents prepared from sodium borohydride, I₂ and a catalytic amount of chiral ferrocenyl amino alcohols 2a-e have been successfully applied to the enantioselective reduction of ketones. The optically active secondary alcohols were obtained in moderate enantiomeric excess and high chemical yield.
- (S)-Ferrocenyl amino alcohol,
- asymmetric reduction,
- enantioselective catalysis,
- NaBH₄/I₂ combination
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