Citation: Wen Qian YANG, Xiao Ming YU, Shi Zhi CHEN, Liang HUANG. Studies on the Total Synthesis of Hainanolide (Ⅳ)-Revising the Stereochemistry of C_2a-H and Introducing the Two Hydroxy Groups at C_3β,C_4α Positions[J]. Chinese Chemical Letters, ;1997, 8(12): 1043-1044. shu

Studies on the Total Synthesis of Hainanolide (Ⅳ)-Revising the Stereochemistry of C_2a-H and Introducing the Two Hydroxy Groups at C_3β,C_4α Positions

Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050

Received Date: 18 September 1997

Fund Project: This project was supported by the National Natural Science Foundation of China.

Tricyclic compound 6 was synthesized from compound 1 through six steps,thus problem of the stereochemistry of C_2a-H being solved.The stereochemistry for introducing hydroxy groups at C_3β and C_4α positions in compound 1 was also described.
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