Citation: Shao Qing CHEN, Jie Chang XU. A NOVEL COUPLING REAGENT (PENTAFLUOROPHENYL DIPHENYLPHOSPHPATE) FOR THE PEPTIDE SYNTHESIS[J]. Chinese Chemical Letters, ;1993, 4(4): 303-306. shu

A NOVEL COUPLING REAGENT (PENTAFLUOROPHENYL DIPHENYLPHOSPHPATE) FOR THE PEPTIDE SYNTHESIS

Shanghai Institute of Organic Chemistry, Academia Sinica 345 Lingling Road, Shanghai 200032

Received Date: 10 September 1992

Fund Project: This work was partly supported by National Key Laboratory of Bio-organic and Natural Products Chemistry.

Pentafluorophenyl diphenylphosphate was found to be a novel convenient coupling reagent for the peptide synthesis with several advantages.Higher yield and lower racemization were found with this reagent than DCCI.
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