Citation: Jia Xi XU, Sheng JIN. NEW HETEROCYCLIC SYSTEM SYNTHESIS VI. THE CYCLOADDITION DERIVATIVES OF 1,5-BENZOTHIAZEPINE AND 1,5-BENZODIAZEPINE[J]. Chinese Chemical Letters, ;1994, 5(7): 557-560. shu

NEW HETEROCYCLIC SYSTEM SYNTHESIS VI. THE CYCLOADDITION DERIVATIVES OF 1,5-BENZOTHIAZEPINE AND 1,5-BENZODIAZEPINE

Jia Xi XU ,
Sheng JIN

Department of Chemistry, Peking University, Beijing 100871

Received Date: 14 April 1994

2,3-Dihydro-1H-1,5-benzodiazepines and 1-benzoyl-2,3-dihydro-1H-1,5-benzodiazepines react with,α-carbonylketenes,generated from 2-diazo-1,3-diphenyl-1,3-propandione or 2-diazo-1-phenyl-1,3-butandione by heating,to give 4a,5,6,12-tetrahydro-1H,7H-1,3-oxazino[3,2-d] [1,5]-benzodiazepine-1-ones,a new ring system.2,3-Dihydro-1H-1,5-benzodiazepines also afford adducts of H-N bond with α-carbonylkelenes,2-aryl-1-(2-benzoyl-phenylacetyl)-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepines.Addition of benzonitrile N-phenylimine,yielded in situ from the N-phenyl benzenecarbohydrazonic chloride,to 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines and 1H-1,5-benzodiazepine gave 3a,5-diaryl-1,3-diphenyl-3a,4,5,11-tetrahydro-3H-1,2,4-triazolo[4,3-d] [1,5]benzothiazepine and 3H,6H-1,2,4-triazolo[4,3-d] [1,5]benzodiazepine,respectively.
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