Citation: Wei Gang LU, Jing Yu SU, Long Mei ZENG, Hong LI. The Effect of 19-Substituent on the Stereospecific Hydroxylation of Δ⁵-Steroids Using Performic Acid as Oxidant[J]. Chinese Chemical Letters, ;2004, 15(8): 899-902. shu

The Effect of 19-Substituent on the Stereospecific Hydroxylation of Δ⁵-Steroids Using Performic Acid as Oxidant

School of Chemistry and Chemical Engineering, Sun Yat-sen(zhongshan) University, Guangzhou 510275

Received Date: 9 July 2003

Fund Project: We are grateful to the National Natural Science Foundation of China (Project No.29932030) and Youth teacher foundation of Sun Yat-sen (Zhongshan) University (Project No.1131002) for financial support for this work.

In the studying of the stereospecific hydroxylation of different Δ⁵-steroids with performic acid, followed by hydrolysis with CH₃OH/KOH, we found 19-substituting groups considerably affected the reaction and we put forward the mechanism.
- Δ⁵-Steroids,
- performic acid,
- 19-substituting group,
- hydroxylation
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