Citation: Xiao Liang XU, Wei Min ZHU, Yong Min ZHANG. The Reductive Addition Reaction of Substituted 2-Chloromethyl-1,3,4-oxadiazole to Aldehydes and Ketones Promoted by Samarium Diiodide[J]. Chinese Chemical Letters, ;2005, 16(12): 1566-1568. shu

The Reductive Addition Reaction of Substituted 2-Chloromethyl-1,3,4-oxadiazole to Aldehydes and Ketones Promoted by Samarium Diiodide

1.
Department of Chemistry, Zhejiang University, Xixi Campus, Hangzhou 310028;
2.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032

Received Date: 28 March 2005

Fund Project: We are grateful to the National Natural Science Foundation of China (Project No.20072033), and the NSF of Zhejiang Province for financial support.

1-(β-Hydroxyalkyl)-1,3,4-oxadiazole derivatives were synthesized via reductive addition reactions of 2-chloromethyl-1,3,4-oxadiazole with carbonyl compounds under mild condifons promoted by SmI₂.
- Reductive addition,
- samarium diiodide,
- 1-(β-hydroxyalkyl)-1,3,4-oxadiazole deriva-tives,
- synthesize
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