Citation: Yi Ming LIU, Feng Xin WANG, Sui Ping DENG, Jian Ming OUYANG. The Effect of Potassium Citrate on Simultaneous Growth of Calcium Oxalate Mono-, Di-, and Trihydrate in Synthetic Urine[J]. Chinese Chemical Letters, ;2006, 17(5): 687-690. shu

The Effect of Potassium Citrate on Simultaneous Growth of Calcium Oxalate Mono-, Di-, and Trihydrate in Synthetic Urine

Institute of Biomineralization and Lithiasis Research, Jinan University, Guangzhou 510632

Received Date: 23 November 2005

Fund Project: This research work was granted by the National Natural Science Foundation of China (No. 20471024).

The inducing effect of potassium citrate (K₃cit) on simultaneous growth of calcium oxalate mono-(COM), di-(COD), and trihydrate (COT) crystals in synthetic urine was observed with double diffusion gelatinous technique. K₃cit can induce the formation of COD and COT, inhibit the aggregation and decrease the surface area of COM crystals. It supported the clinical use of K₃cit and may provide important clues to this disease in cure and in search for new drugs.
- Calcium oxalate,
- potassium citrate,
- biomineralization,
- urinary stone,
- gel
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