Citation: Zhan Zhu LIU, Shi Zhi CHEN. Synthetic Studies of Et-743, Preparation of A Racemic Amino Alcohol Precursor[J]. Chinese Chemical Letters, ;2003, 14(11): 1127-1129. shu

Synthetic Studies of Et-743, Preparation of A Racemic Amino Alcohol Precursor

Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050

Received Date: 6 November 2002

A mild two-step method was used to cleave the lactam ring of the tricyclic intermediate 1. A key racemic amino alcohol precursor 5 for the construction of Et-743 skeleton was synthesized from 1 through four steps in total yield of 47%.
- Et-743,
- lactam,
- cleavage
1. [1]
  Yan Cheng , Hua-Peng Ruan , Yan Peng , Longhe Li , Zhenqiang Xie , Lang Liu , Shiyong Zhang , Hengyun Ye , Zhao-Bo Hu . Magnetic, dielectric and luminescence synergetic switchable effects in molecular material [Et₃NCH₂Cl]₂[MnBr₄]. Chinese Chemical Letters, 2024, 35(4): 108554-. doi: 10.1016/j.cclet.2023.108554

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