Citation: Jing Chao DONG, Run Tao LI, Tie Ming CHENG. One-Pot Synthesis of N-Boc-2, 5-bis(trimethylsilyl)pyrrolidine[J]. Chinese Chemical Letters, ;2001, 12(12): 1061-1064. shu

One-Pot Synthesis of N-Boc-2, 5-bis(trimethylsilyl)pyrrolidine

Department of Bioorganic Chemistry, School of Pharmaceutical Sciences, Peking University, Beijing 100083

Received Date: 20 April 2001

Fund Project: This work is supported by the National Natural Science Foundation of China (No.29772004).

N-Boc-2, 5-bis(trimethylsilyl)pyrrolidine 4 was synthesized from the reaction of N-Boc-pyrrolidine 1 with trimethylsilyl chloride (TMSCl) at optional temperature in one-pot in good yield.
- N-Boc-2,5-bis(trimethylsilyl)pyrrolidine,
- trimethylsilylation,
- one-pot
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