Citation: Shao Qing CHEN, Jie Cheng XU. SYNTHESIS OF CYCLIC PEPTIDES USING BBC REAGENT[J]. Chinese Chemical Letters, ;1993, 4(10): 847-850. shu

SYNTHESIS OF CYCLIC PEPTIDES USING BBC REAGENT

Shanghai Institute of Organic Chemistry, Academia Sinica, Shanghai 200032

Received Date: 31 May 1993

Fund Project: This work was supported by State Key Laboratory of Bio-organic and Natural products Chemistry.

We report here the synthesis of cyclic peptides using benzotriazolyloxy-bis (pyrrolidino)-carbonium hexafluoro-phosphate (BBC) as a coupling reagent with high yield and speed even in low concentration compared with the other usual coupling reagents.
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