Citation: Jin JIANG, Jiu Yu LIU, Hui Yuan GUO. Synthesis of Quinolone Analogues: 7-[2-Aminomethylaziridin-1-yl]-quinolones[J]. Chinese Chemical Letters, ;2006, 17(11): 1431-1434. shu

Synthesis of Quinolone Analogues: 7-[2-Aminomethylaziridin-1-yl]-quinolones

Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050

Received Date: 13 September 2006

Fund Project: The authors would like to thank the National Research Center of Drug and Metabolite Analysis for measuring the data of 1H NMR, ESI-MS and HRESI-MS. We also want to thank the pharmacology laboratory of Institute of Medicinal Biotechnology for testing the antibacterial activity.

New quinolone derivatives of 7-[2-aminomethylaziridin-1-yl]quinolone-3-carboxylic acids were synthesized. The structures of these compounds were characterized by ¹H NMR and HRESI-MS.
- Aziridine,
- quinolone,
- synthesis
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