Citation: Hao HONG, Dao Fei HUANG, Liang HUANG. STUDY ON THE INTRAMOLECULAR CVCLIZATION THROUGH OPENING OF EPOXIDE II RING CLOSURE OF N-METHYL-N-BENZOYLMETHYLENE-β-PHENYL-α,β-EPOXYPROPIONAMIDE IN PROTIC SOLVENT[J]. Chinese Chemical Letters, ;1993, 4(12): 1037-1038. shu

STUDY ON THE INTRAMOLECULAR CVCLIZATION THROUGH OPENING OF EPOXIDE II RING CLOSURE OF N-METHYL-N-BENZOYLMETHYLENE-β-PHENYL-α,β-EPOXYPROPIONAMIDE IN PROTIC SOLVENT

Institute of Materia Medica, Chinese Academy of Medical Sciences, Xian Non Tan St, Beijing 100050

Received Date: 27 August 1993

Fund Project: This work was supported by the Doctorate Program of The State Education Commission of China.

When the title compound was treated in protic solvent with alkali catalyses, γ-lacatam was almost the sole product. The ratio of ketone 1 to ketone 2 depended upon the reaction condition.
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