Citation: Jing LI, Jiong LAN, Zuo Sheng LIU, Yu Lin LI. The First Total Synthesis of Five Elegan Type Natural Products[J]. Chinese Chemical Letters, ;1997, 8(7): 595-598. shu

The First Total Synthesis of Five Elegan Type Natural Products

National Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000

Received Date: 17 March 1997

Fund Project: This work was financially supported by the National Natural Science Foundation of China (Grant No. 29672015) and the Special Research Grant for Doctoral Sites in Chinese Universities.

The first total synthesis of five linear diterpenes:eleganolone (1),eleganolone acetate (2),elegandiol (3),eleganonal (4) and epoxyeleganolone (5),was achieved from (E,E)-farnesol (6) via 4 to 6 steps.The key step was the alkylation reaction of silyl cyanide with allylic iodide.
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