Citation: Ping Zhen WANG, Yan Xing JIA, Yong Qiang TU, Bin WU. Synthetic Studies of an Analogue of HIV-1 Protease Inhibitors of Didemnaketals:Construction of the C1-C8 Intermediate[J]. Chinese Chemical Letters, ;1999, 10(9): 749-750. shu

Synthetic Studies of an Analogue of HIV-1 Protease Inhibitors of Didemnaketals:Construction of the C1-C8 Intermediate

Department of Chemistry, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000

Received Date: 7 April 1999

A convenient and stercoselcctive approach to the synthesis of (3S. 4R, 6S)-2-oxo-3.4-dihvdrosy-6-methyl-octanatc derivative. a kcy intermediate for the synthesis of IIIV-1 protease inhibitor of didcmnaketals analogue, has been developed successfully from L-(-)-mcnthone.
- Didemnaketals,
- 2-oxo-3,
- 4-dihydroxy-6-methyl-octanate,
- steroselective synthesis
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