Citation: Qiang YIN, Zhen ZHA NG, Yu Fen ZHAO. DNA Binding and Cleavage Property of Pyrenyl-macrocyclic Polyamine Conjugate[J]. Chinese Chemical Letters, ;2006, 17(9): 1185-1188. shu

DNA Binding and Cleavage Property of Pyrenyl-macrocyclic Polyamine Conjugate

The Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology(Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084

Received Date: 27 March 2006

Fund Project: The authors wish to acknowledge the financial support from the National Natural Science Foundation of China (No. 20132020), the National Science and Technology Committee of China, Chinese National Ministry of Education and Tsinghua University

We reported the synthesis of a simple bifunctional molecule and the interaction between this molecule and DNA were studied by UV and the DNA cleavage behavoior was determined by agarose gel electrophoresis.
- DNA cleavage,
- ESI-MS,
- UV,
- agarose gel electrophoresis
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