Citation: Jing Shan SHEN, Li Jun LEI, Tie Ma YAN, Jian Feng LI, Hui Jun LI, Zhen Hua LI, Ru Yun JI. Synthesis of 2-Substituted Hexahydro-1H-1,4-diazepine Analogues[J]. Chinese Chemical Letters, ;2001, 12(3): 193-194. shu

Synthesis of 2-Substituted Hexahydro-1H-1,4-diazepine Analogues

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031

Received Date: 14 August 2000

2-substituted hexahydro-1H-1,4-diazepine analogues were synthesized starting from N,N-dibenzyl-1,3-propylene diamine and methyl-2,3-dibromo propionate through nucleophilic substitution, reduction, chlorination and debenzylation.
- Hexahydro-1H-1,4-diazepine analogues,
- synthesis,
- nucleophilic substitution,
- reduction,
- chlorination,
- debenzylation
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