Citation: Nong Yue HE, Hui Shi GUO, Di YANG, Chun Rong GU, Ji Nan ZHANG. SBA-15 Modified Carbon Paste Electrode for Rapid cTnI Detection with Enhanced Sensitivity[J]. Chinese Chemical Letters, ;2006, 17(2): 235-238.
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A novel electrochemical immunoassay for cardiac troponin I (cTnI) combining the concepts of the dual monoclonal antibody "sandwich" principle, the silver enhancement on the nano-gold particle, and the SBA-15 mesoporous modified carbon paste electrode (SBA-MCPE) is described. Four main steps were carried out to obtain the analytical signal, i.e., electrode preparation, immunoreaction, silver enhancement, and anodic stripping voltammetric detection.A linear relationship between the anodic stripping peak current and concentration of cTnI from 0.5 to 5.0 ng/mL and a limit of detection of 0.2 ng/mL of cTnI were obtained.
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