Citation: Yue Dong YANG, Jiu Gao YU, Yong Guo ZHOU, Pei Guo LI. Preparation and Blood Compatibility of Oxidized-chitosan Films[J]. Chinese Chemical Letters, ;2005, 16(7): 991-994. shu

Preparation and Blood Compatibility of Oxidized-chitosan Films

1.
Department of Chemistry, Hebei Normal University of Science & Technology, Changli 066600;
2.
Department of Chemistry, School of Science, Tianjin University, Tianjin 300072

Received Date: 23 August 2004

Fund Project: Financial support for this work from Natural Science Foundation of Hebei Province (No. B2004000402).

Chitosan membrane was modified by the selective oxidization of chitosan molecules on its surface with NO₂ gas. FTIR spectra indicated there were plenty of-COOH and-COO^- groups on the modified membrane surface. The SEM study showed the modified membrane surface was rough rather than smooth as chitosan membrane. All antithrombosis test, hemolysis test and blood cell morphology observation with SEM revealed that modified chitosan membranes have superior blood compatibility to chitosan.
- Chitosan,
- blood compatibility,
- modified chitosan membrane,
- nitrogen dioxide
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