Citation: An Pai LI, Hui WANG, Cheng Lu ZHANG, Tong Xing WU, Xin Fu PAN. First Total Synthesis of an Analogue of (±)-Hypargenin B[J]. Chinese Chemical Letters, ;2002, 13(2): 133-134. shu

First Total Synthesis of an Analogue of (±)-Hypargenin B

Department of Chemistry, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000

Received Date: 4 June 2001

Fund Project: We are grateful to the National Natural Science Foundation of China (No.29372050) for financial support.

First total synthesis of (±)-hypargenin B methyl ether 2 was accomplished via a strategy of AC→ABC, in which CrO₃/H₂O/NaOAc/HOAc system was utilized for introducing 7-keto group in order to avoid dehydration of benzyl tertiary alcohol.
- Hypargenin B,
- diterpene,
- intramolecular,
- steroselective
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