Citation: Wei Shuo FANG, Qi Cheng FANG, Xiao Tian LIANG. Preliminary Studies on Acylation of 10β-OH and 7α-OH in 7-Epi-10-deacetylpaclitaxel[J]. Chinese Chemical Letters, ;1997, 8(10): 847-848.
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10β-OH can be acylated cleanly when 7α-OH is also free,and thus a facile access to semi-synthesis of 7-epi-paclitaxel was proposed.A 2's,3's-oxazoline paclitaxel analog was serendipitously synthesized.
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