Citation: Lun Jia XIE. A FACILE SYNTHESIS OF CHIRAL 3-ALKYL-3,4-DIHYDRO-2H-1,4-BENZOXAZINE DERIVATIVES[J]. Chinese Chemical Letters, ;1995, 6(10): 857-860. shu

A FACILE SYNTHESIS OF CHIRAL 3-ALKYL-3,4-DIHYDRO-2H-1,4-BENZOXAZINE DERIVATIVES

Lun Jia XIE

National institute of Pharmaceutical Research and Development shahe, Beijing 102206

Received Date: 24 March 1995

Fund Project: I am indebted to Prof. Luo Xuande for his encouragement and support of this work.I would like to thank Ms. Wang Xuefeng for obtaining mass spectra.I also thank Prof.Shen Jiaxiang, Prof. Zhuang Lingen and Prof. Zhao Shuwei for helpful discussions during the preparation of this manuscript.

This paper describes a facile synthesis of chiral 3-alkyl-3,4-dihydro-2H-1,4-benzoxazine derivatives 1,in which (S) or (R) configuration (1b or 1c)is obtainable.
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