Citation: Feng ZHANG, Fang MEI, Xin Zhi WANG, Xiao Yang HU, Yong Ming LUO, Xu Liang DENG. A New Route for Preparation of β-TCP/PLLA Composite[J]. Chinese Chemical Letters, ;2006, 17(6): 833-836. shu

A New Route for Preparation of β-TCP/PLLA Composite

1.
School and Hospital of Stomatology, Peking University, Beijing 100081.;
2.
Department of Histology and Embryology, Health Science Center, Peking University, Beijing 100083;
3.
Department of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650093;
4.
The 2nd Hospital of Beijing Armed Police Forces, Beijing 100037

Received Date: 7 November 2005

Fund Project: We gratefully acknowledge the support of this research work by National High Technology Research and Development Program of China (No. 2003AA302220, 2004AA304G50) and the National Natural Science Foundation of China (No. 30471907).

A new facile route for preparation of β-TCP/PLLA composites is reported in this letter.SEM images display that β-TCP particles with average diameter of 400 nm were well bonded and distributed within the pore walls of the PLLA scaffolds. The mixture of the novel complex and human dental pulp cells was transplanted subcutaneously into the dorsal surface of a nude mouse.Two months later histological examination showed that new collagen and new dentin formed.The results revealed that the new nano β-TCP/PLLA composite combined with human pulp cells could induce dentin formation, offering a new way to dental tissue engineering.
- β-TCP particles,
- β-TCP/PLLA composite,
- dental pulp cells,
- dental tissue engineering
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