Citation: Guang Yan HUANG, Yu GUO, Xiao Tian LIANG. Homologation of Taxol Side Chain via Arndt-Eistert Reaction Involving the Wolff Rearrangement[J]. Chinese Chemical Letters, ;1996, 7(12): 1077-1078. shu

Homologation of Taxol Side Chain via Arndt-Eistert Reaction Involving the Wolff Rearrangement

Institute of Materia Medica Chiners Academy of Medical Sciencs &Peking Union Medical College Beijing 100050

Received Date: 21 August 1996

Homologation of protected taxol side chain Homologation of protected taxol side chain 8 from 4 was accomplished stereospecifically through the key intermediate diazo ketone 5 which was actually isolated.The structures of 5 and 7 were identified by spectrometric methods,mainly ¹H-NMR,IR,¹³C-NMR and DEPT techniques.
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