Citation:
Xu Lu, Yao Yuyuan. The Kelationship Between Activities and Conformations of Steroids[J]. Chinese Journal of Applied Chemistry,
;1995, 12(1): 59-62.
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The molecular mechnics calculation has been performed for conformation analysis of steroids, The results reveal that there are two factors which importantly influence the ac-tivity of the steroids,namely the specific substitution sites(R1 and R2) and the steric posi-tion and energy of oxygen atoms in the compounds.
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Keywords:
- steroid,
- activity conformation,
- molecular mechanics
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