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Citation: Shi Feng, Xiao Yanwen, Ni Jiazuan. DETERMINATION OF PROTON DISSOCIATION CONSTANT OF TRIS-(HYDROXYMETHYL)-AMINOMETHANE BY NMR METHOD[J]. Chinese Journal of Applied Chemistry, ;1986, 3(6): 68-69. shu

DETERMINATION OF PROTON DISSOCIATION CONSTANT OF TRIS-(HYDROXYMETHYL)-AMINOMETHANE BY NMR METHOD

1.
Changchun Institute of Applied Chemistry, Academia Sinica

Received Date: 26 December 1985
Available Online: 10 March 1986

The proton dissociation process of tris- (hydroxymethyl) -aminomethane(THAM)has been studied by ¹H and ¹³C NMR methods.The proton dissociation constant of thetitle compound determined was pK=8,15, which was in good agreement with the re-sults obtained by other methods in the literature.
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