Citation:
Shi Feng, Xiao Yanwen, Ni Jiazuan. DETERMINATION OF PROTON DISSOCIATION CONSTANT OF TRIS-(HYDROXYMETHYL)-AMINOMETHANE BY NMR METHOD[J]. Chinese Journal of Applied Chemistry,
;1986, 3(6): 68-69.
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The proton dissociation process of tris- (hydroxymethyl) -aminomethane(THAM)has been studied by 1H and 13C NMR methods.The proton dissociation constant of thetitle compound determined was pK=8,15, which was in good agreement with the re-sults obtained by other methods in the literature.
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