Citation:
Yan Jiangli, Wu Shouguo, Pu Guogang, Wang Erkang. DETERMINATION OF 5-FLOUROURACIL IN SERUM BY CATHODIC STRIPPING VOLTAMMETRY AND MECHANISM OF ELECTRODE REACTION[J]. Chinese Journal of Applied Chemistry,
;1992, 9(1): 37-41.
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The differential pulse cathodic stripping voltammetry has been employed to determine the concentration of 5-flourouracil (5-Fu) in serum.The interferences of electroactive substanees in serum can be eliminated by trichloroacetic acid. It is shown that 5-Fu can combine with Hg(Ⅱ) generated by anodic polarization forming an insoluble complex on electrode surface, The Hg-5-Fu complex is deemed to be a macromolecule with chain structure.
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Keywords:
- cathodic stripping voltammetry,
- 5-flourouracil,
- serum,
- mechanism
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