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Citation: Chen Weimin, Wan Shanhe, Xu Jihong, Zeng Longmei. Synthesis of 2-(2-Methoxyphenoxy) ethylamine[J]. Chinese Journal of Applied Chemistry, ;1999, 16(6): 100-101. shu

Synthesis of 2-(2-Methoxyphenoxy) ethylamine

1.
a Institute of Pharmaceutical Sciences, The First Military Medical University, Guangzhou 510515;
2.
b Department of Chemistry, Zhongshan University, Guangzhou

Received Date: 8 March 1999
Available Online: 14 July 1999

A new route for the synthesis of the title compound from phthalic anhydride and monoethanolamine is reported.The N-hydroxyethylphthalimide(2) could be reacted directly with HBr without being isolated to give N-bromoethylphylphalimide(3), which reacting with guaiacol by phase transfer catalysis gave O-methoxyphenoxyethyl phthalimide(4).The title compound was then obtained after its hydrolysis.
- methoxyphenoxy-ethylamine,
- synthesis
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