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Citation: LIU Wen-Min, SUN Ru-Zhong, YAO Xing-Zhi, YANG Hao, XING Wen-Ru, CHEN Wen-Tao, HUI Feng-Li. Synthesis and Biological Activity of N,N'-Nitrobenzoyl Substituted-benzoylthiosemicarbazides[J]. Chinese Journal of Applied Chemistry, ;2002, 19(4): 393-395. shu

Synthesis and Biological Activity of N,N'-Nitrobenzoyl Substituted-benzoylthiosemicarbazides

1.
a Department of Chemistry, Nanyang Teachers College, Nanyang 473061;
2.
b Department of Biology, Nanyang Teachers College, Nanyang 473061

Corresponding author: LIU Wen-Min,
Received Date: 27 June 2001
Available Online: 18 October 2001
Fund Project: 河南省教委科技攻关项目(1999150035) (1999150035)

Twentyone N,N'-nitrobenzoyl substituted benzoylthiosemicarbazides were synthesized by addition reaction of nitrophenyl isothiocyanates with aroyl hydrazines and their structures were characterized by ¹H NMR, ¹³C NMR, IR and elemental analysis. The biological tests indicated that these compounds had antibacterial activity against B.subtilis, but no action on E.coli.
- acylthiosemicarbazide,
- aroylhydrazine,
- synthesis,
- antibacterial activity
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