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Citation: ZHANG Xiang-Zhu, ZHANG Ji-Chang, WU Ming-Shu. Synthesis of N-Methylmorpholine[J]. Chinese Journal of Applied Chemistry, ;2003, 20(9): 917-918. shu

Synthesis of N-Methylmorpholine

1.
Department of Chemical Engineering, Anyang University, Anyang 455000

Corresponding author: ZHANG Xiang-Zhu,
Received Date: 10 January 2003
Available Online: 23 May 2003
Fund Project: 安阳市科委2000年资助项目(200064) (200064)

N-Methylmorpholine was synthesized by alkylation of morpholine with chloromethane in sodium hydroxide solution. The influences of reaction temperature, reaction time and molar ratio of reactants on the yield of the reaction were examined. The optimum reaction conditions are as follows:reaction temperature 35℃, time 5 h, n(morpholine):n(monochloromethane)=1:1.1, n(morpholine):n(sodium hydroxide)=1:1.2, yield of N-methylmorpholine 85%, purity 98%.
- N-methylmorpholine,
- synthesis,
- monochloromethane
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