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Citation: LIU Lin-Xue, CHEN Bao-Rong, LIU Yi-Feng. Synthesis of 2,6-Dihydroxy toluene[J]. Chinese Journal of Applied Chemistry, ;2004, 21(10): 1075-1077. shu

Synthesis of 2,6-Dihydroxy toluene

1.
a Institute of Applied Chemistry, Northwest University, Xi'an 710069;
2.
b Shaanxi Goldsun Chemical Co. Ltd, Xi'an

Corresponding author: LIU Lin-Xue,
Received Date: 18 November 2003
Available Online: 4 March 2004
Fund Project: 陕西省教育厅资助项目(03JC01) (03JC01)

2,6-Dihydroxy toluene was synthesized from resorcinol in 4 steps:alkylation, methylacylation, Huang Ming-Long reaction and dealkylation. In first two steps ethylene dichloride was used as the solvent. This made the two reactions easy and the yields high, and also decreased the amount of DMF used in second step. The third step was a modified Huang Ming-Long reaction carried out at more mild condition. The total yield of the title compound was 62%.
- dihydroxy toluene,
- resorcinol,
- ethylene dichloride,
- alkylation,
- methylacylate,
- Huang Ming-Long reaction,
- dealkylation
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